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Human Resources (HR) Director

ClearNote Health clearnotehealth.com Open
San Diego Full-time Director HR Business Partner & Generalist

At a glance

Director-level HR Business Partner & Generalist role at ClearNote Health. San Diego · full-time · $175,000–$220,000 base.

SalaryStated by ClearNote Health
$175,000 – $220,000
Base salary for this role, in USD per year, as published in the posting.
RoleHR Business Partner & Generalist
SeniorityDirector
LocationSan Diego
EmploymentFull-time
Base pay$175,000–$220,000
PostedOct 29, 2026
Role brief

hrroles summary, based on the employer's posting.

What you'll do

  • Set HR programs across hiring, pay, benefits, performance, employee relations and staff development
  • Lead culture and values work, while shaping internal communications through meetings, written updates and training
  • Run hiring from sourcing and resume review through interviews, selection and onboarding
  • Build manager skills and training, and advise leaders on employee issues and organizational effectiveness
  • Maintain HR policies, records and systems, and keep programs aligned with legal requirements

What you bring

  • A bachelor’s degree is required; a master’s or HR certification is preferred
  • You bring eight to twelve years in HR, including three to five years leading staff directly
  • You know core HR areas such as staffing, employee relations, compensation, benefits and training
  • You can work across multiple employee locations and guide teams through organizational change

Who this fits

This director role suits an independent HR leader who can cover both strategic work and day-to-day administration. You’ll lead a team with direct reports and support employees across two work locations as well as remote staff. Life sciences experience is preferred.

From the employer

ClearNote Health is an early cancer detection company focused on the development and commercialization of non-invasive epigenomic tests to detect cancer through a standard blood draw, earlier than existing methods and when the disease is still treatable. Leveraging its novel liquid biopsy technology, ClearNote Health is initially focused on high-mortality cancers with the greatest need for early detection, starting with pancreatic and ovarian cancers.

Position Summary:
The HR Director leads the Human Resources function, aligning HR strategy with business objectives, managing HR operations, and fostering a strong workplace culture. This position will provide HR direction and support for the entire organization, which includes two work locations and remote employees. Plan and develop programs to ensure the company is able to attract and motivate an effective team. Partner with the executive team for company-wide initiatives, including the organization’s culture and values, internal communications and growth/change leadership. Must have a solid track record of building strong partnerships with all employee levels and the proven ability to develop and implement successful programs. Must be independent and capable of handling HR in its entirety, from strategy to administrative responsibilities.

Key Responsibilities:
  • Plan and implement human resources programs for areas including staffing, compensation, benefits, performance management, employee relations, and leadership/employee development.
  • Provide leadership and training for the company’s culture and values, with a focus on sustaining a strong, collaborative environment.
  • Responsible for internal communications which may include design of systems such as an intranet site, employee meetings, written communications, and training and presentations on corporate initiatives and company values.
  • Provide advice and counsel for problem solving, issue resolution and other organizational effectiveness needs.
  • Manage recruitment and selection methods, as well as on-boarding programs. This includes sourcing, job postings, resume review and being an active leader and participant in the interview and selection process.
  • Implement and manage performance management programs and develop manager capabilities.
  • Identify and develop manager and employee training programs, with appropriate timing and relevance to the company’s needs and strategy.
  • Establish, design and maintain competitive compensation, benefits, and other reward and recognition programs.
  • Create, interpret and implement HR policies and processes as appropriate for the business needs.
  • Partner with and provide guidance as needed for functions/positions such as Payroll, Administrative, Facilities, and IT to provide a consistent employee experience.
  • Maintain employee records and systems and conduct other basic administrative tasks as required by the function.
  • Maintain up to date knowledge of best HR practices and legal requirements, and ensure programs and processes are compliant, consistent and effective.

Qualifications:
  • Bachelor’s degree. Master’s degree and/or HR-related certification(s) strongly preferred.
  • 8-12 years of progressive Human Resources experience, with a minimum of 3-5 years in a leadership role with direct reports. Experience in the life sciences industry preferred.
  • Demonstrated ability to work productively and effectively with executives, leaders, and all levels in the organization and across functional boundaries.
  • Demonstrated success leading through organizational change in a fast-paced environment and fostering a culture of collaboration.
  • Experience working with and establishing programs for an organization with employees at multiple locations.
  • Excellent oral and written communication skills, interpersonal skills, and presentation skills.
  • Strong attention to detail and highly organized.
  • Excellent ability to prioritize, work independently, and multi-task at a fast pace.
  • Demonstrated ability to establish process, policy and programs.
  • Proficient in all areas of Human Resources, including staffing, employee relations, compensation, benefits, organizational development and training.
  • Thorough working knowledge and competency with all Microsoft applications, database management and producing spreadsheets, reports and presentations.

The anticipated salary range for this position is $175,000 to $220,000. The actual salary will be dependent on various factors that may include experience level, knowledge, skills, and abilities.

Come join us in addressing large healthcare needs through precision epigenomic medicine!

ClearNote Health is an exciting life science company that is reinventing non-invasive molecular diagnostic testing using next generation epigenomic technologies. We are passionate and dedicated to discovering and developing medicines that will make a significant difference in cancer and other epigenomic-driven diseases. Our technologies provide novel insight and quantitation of human health and disease, with our focus on precision medicine applications improving both clinical and health system outcomes. Our company was founded based on pioneering work in the Stanford laboratory of Stephen Quake, with advisors from Stanford and UCSF.

We look for extraordinary lifelong learners with a passion and growth mindset for these areas, and for combining biological ingenuity with AI and data analysis. Led by a team with decades of experience bringing products from concept to market, we are an equal opportunity employer and value diversity at our company.

We provide generous benefits to all employees including stock options. We are building a world-class company, based in San Diego and San Mateo.

Our commitment to Diversity, Equity, Inclusion, and Belonging:

We celebrate diversity in perspectives and backgrounds, and this is reflected in our innovation, our mission, and values. Our differences make us unique, help us innovate, and allow us to persevere. We strive to achieve representation and inclusion and redefine the possible in patients living longer lives.

Opportunity

HR Business Partner & Generalist work from LinkedIn, X, Reddit and Upwork, in one list.

Each morning you get everything that fits, strongest first.

HR Business Partner & Generalist$170k+

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By the team behind hrroles.

Find me work
Opportunity

HR Business Partner & Generalist work from LinkedIn, X, Reddit and Upwork, in one list.

Each morning you get everything that fits, strongest first.

Find me work

By the team behind hrroles.